Dogs on a glucocorticoid treatment program often have an increase in thirst and appetite. This side effect is usually followed by an increase in urination (and possible incontinence), stomach upset and weight gain. Steroids can also affect the dog's mood, making it irritable. Dogs also may become lethargic and begin panting incessantly. Steroids can also bring back a latent infection or tip pre-diabetic dogs into a diabetic state. Usually, diabetic symptoms and the other side effects diminish or resolve themselves once the steroid wears off.