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Eye care practitioners can choose from an impressive and effective armamentarium of drugs to combat infectious diseases that are caused by bacteria. In most cases, a combination steroid-antibiotic agent is the best choice to address both the infection (or the threat of infection) and the inflammation that results from bacterial inhabitation. High-dose, potent antibiotic therapy should be reserved only for those serious infectious cases where the cornea is truly threatened and should never be used injudiciously because of the evergrowing risk of antibiotic-resistant organisms.