Secosteroid structure

Figure B shows a picture of a male with Gigantism (over-secretion of growth hormone) who had a final height of nearly 9 feet. Longitudinal bone growth occurs at the growth plate by a process called endochondral ossification in which cartilage is first formed and then remodeled into bone tissue. The growth plate consists of three principal layers: the resting zone, proliferative zone, and hypertrophic zone. Growth hormone acts preferentially at the proliferative zone where it stimulates longitudinal bone growth.
Figure A represents Spondyloepiphyseal dysplasia (SED) where there is disproportionate dwarfism, spinal involvement, and a barrel chest from a COL2A1 mutation. Figure C represents diastrophic dysplasia with a "hitch-hikers" thumb, "cauliflower ear", cleft palate, and short-limbed dwarfism due to a sulfate transport mutation. Figure D represents cleidocranial dysplasia due to defect in core-binding factor alpha 1 (CBFA-1) causing dwarfism and absent clavicles. Figure E represents Multiple epiphyseal dysplasia (MED) causing disproportionate dwarfisim with multiple epiphyses involved, shortened metacarpals, valgus knees, but no spinal involvement, all of which are due to a COMP mutation.

“One nanomolar levels ‘of Thimerosal’ in the baby will prevent the macrophages from going through phagocytosis (vaccines using Thimerosal as a preservative contain 125,000 nanomolar level of mercury). In other words, they will lose their ability to eat viruses and bacteria that are in the blood that shouldn’t be there, and so Thimerosal suppresses the immune system. This is well known and has been well described in the literature for a long time; that mercury is an immune system suppressor and you see that these autistic children have a truckload of immune problems. So you would prevent that from occurring. That is documented research and I don’t know how the government can even ignore it, or the agencies of the government can ignore it. ” Dr. Boyd Hayley

Secosteroid structure

secosteroid structure


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