Intralesional steroid side effects

Levine and Rasmussen (1983) evaluated the effectiveness of intralesional injections of corticosteroids in the therapy for nodulo-cystic acne.  Triamcinolone acetonide at a concentration of mg/ml was as effective as a higher concentration of mg/ml.  Betamethasone phosphate had little, if any, effect on nodulo-cystic acne lesions at concentrations of , , and mg/ml, when compared with saline controls.  Mahajan and colleagues (2003) compared the effectiveness of intralesional triamcinolone with that of a combination of intralesional lincomycin and intralesional triamcinolone in nodulo-cystic acne.  A total of 10 patients of nodulo-cystic were injected with intralesional triamcinolone acetonide ( mg/ml), while 9 patients were given lincomycin hydrochloride (75 mg/ml) in addition to the intralesional triamcinolone.  They were followed-up 48 hours, 1 week and 1 month later.  At 1 week, 7 patients (70 %) treated with injection triamcinolone showed 66 % improvement, whereas all 9 (100 %) patients treated with lincomycin and triamcinolone showed 100 % improvement that was stable at 1 month.  The authors concluded that c combination of intralesional triamcinolone and lincomycin is superior to intralesional triamcinolone alone in the treatment of nodulo-cystic lesions of acne.

Intralesional steroid side effects

intralesional steroid side effects

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